Medicinal Plant Lexicon

Medicinal Plant Lexicon

Onion

Onion
Photo: Sertürner Bildarchiv

Botanical name

Allium cepa L.

Family

Amaryllidaceae

Common name

Garden onion, Common onion

Information about the plant

Onion
Photo: Stahl-Biskup

The onion is a cultivated plant that has been used since prehistoric times. Originally native to Central Asia (Afghanistan), it is now cultivated in countless varieties and grown worldwide every year. Annual production amounts to several million tons.

The genus name Allium is derived from the Latin word ‘allium’ (= leek, garlic), because leeks were a popular spice and food in Rome and the rest of Italy, as well as in the East, at least among the common people. The species epithet cepa also comes from Latin and means ‘onion’.

The garden onion (Allium cepa), as used in cooking, is the strongly compressed shoot axis of the plant, whose leaf sheaths are fleshy and swollen. It develops when a bulb is planted in the ground for propagation. This forms roots that sprout downward and green upper leaves that sprout upward to ensure energy production. It then reproduces by means of side buds, whose shoot tips repeatedly form new leaves. These are arranged in a shell-like pattern and swell strongly in the lower area, thus forming new onions. If an onion is cut lengthwise, the firm onion disc (= compressed shoot axis) can be seen in the middle, surrounded by fleshy, thickened leaf sheaths, often with daughter onions (= side buds) between them. The outer leaves gradually die off and form a dry, brown, paper-like shell (“skin”). If the plant is allowed to develop unhindered, it forms white flowers that stand in a spherical inflorescence. In cultivation, the inflorescences are removed so that the storage compounds in the bulb are not used for seed formation.

Medicinally used parts of plants (herbal drug)

The fresh, chopped onions, or dried onions in powder form (onion – Allii cepae bulbus) are used.

Constituents of the herbal drug

Fresh onions contain various alliin compounds, primarily isoalliin, which comes into contact with the enzyme alliinase when the onion is chopped. This hydrolyzes it into prop-1-enylsulfenic acid, which is partially converted into the tear-inducing thiopropanal-S-oxide. Onions also contain flavonoids, γ-glutamyl peptides, phenols, vitamins, and carbohydrates.

Quality of the drug

No pharmacopoeial quality description is available for onion (Allii cepae bulbus).

Medical applications

Recognised medical use

HMPC: The monograph was rejected because classification as a medicinal product with recognized medical efficacy (well-established use) and as a traditional herbal medicinal product (traditional use) could not be supported.

ESCOP: Onion has not yet been evaluated.

Traditional use

Not classified as a traditional herbal medicinal product (Article 16a of Directive 2001/83/EC).

Herbal drug preparations in finished dosage forms

Freshly pressed plant juice

Dosage

50 g fresh or 20 g dried onions per day, prepared accordingly.

Onions are also commonly used to treat coughs and colds. Onion juice can be mixed with honey for this purpose. For young children, chopped onions can also be placed around the room, allowing the volatile sulfur compounds to enter the respiratory tract.

Preparation of a tea

Not applicable.

Notes

Eating onions can alter the smell of the skin and breath.

Side effects

Lower abdominal discomfort, such as flatulence and bloating, may occur.

Interactions

None known.

References

Herbal drug monographs

HMPC (2012), WHO Vol. 1

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